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Review Article | OPEN ACCESS

Medicinal uses, phytochemistry, pharmacology and toxicological properties of Elaeodendron croceum

Alfred Maroyi

http://dx.doi.org/10.4314/tjpr.v18i3.30;

For correspondence:-     Email: amaroyi@ufh.ac.za   Tel:+27719600326

Accepted: 24 February 2019        Published: 31 March 2019

Citation: Maroyi A. Medicinal uses, phytochemistry, pharmacology and toxicological properties of Elaeodendron croceum. Trop J Pharm Res 2019; 18(3):669-676 doi: 10.4314/tjpr.v18i3.30

© 2019 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Elaeodendron croceum is a shrub or a small tree used as an emetic, purgative and herbal medicine for cough, sore throat, fever, tuberculosis, blood in sputum, chest congestion, human immunodeficiency virus (HIV) opportunistic infections and to clean the digestive tract. Phytochemical compounds identified from the species include alkaloids, cardiac glucoside, flavonoids, phenols, proanthocyanidins, saponins, sugars, tannins and triterpenoids. Pharmacological studies revealed that E. croceum extracts and compounds have antimycobacterial, anti-arthritic, antibacterial, anti-HIV, antioxidant, anti-in@258;ammatory, antifungal and cytotoxicity activities. Future studies should focus on ethnopharmacological safety and efficacy of E. croceum extracts and compounds isolated from the species using in vivo preclinical studies and clinical trials.

Keywords: Celastraceae, Elaeodendron croceum, Herbal medicine, Southern Africa, Traditional medicine

Impact Factor
Thompson Reuters (ISI): 0.523 (2021)
H-5 index (Google Scholar): 39 (2021)

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